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爱思唯尔期刊精选全文
标题：炎性肠疾病治疗规范：“自上而下”与“拾级而上”
Gastroenterology Clinics of North America, 2009, Volume: 38, Issue: 4
作者：Shane M. Devlin MD and Remo Panaccione MD
内容预览：
Crohn disease (CD) and ulcerative colitis (UC) comprise a group of inflammatory disorders of the gastrointestinal tract that can vary in severity of disease, anatomic extent of inflammation, presence and nature of extraintestinal manifestations, and response to therapeutic approaches. There have been attempts to classify CD based on the location and behavior of disease. Advances in understanding of genetic susceptibility to inflammatory bowel disease (IBD) suggest that CD and UC may represent a continuum of overlapping disorders. This has led to an attempt to classify IBD on clinical, molecular, and serologic grounds. Differences in clinical, genetic, and immunologic profiles may require more targeted, refined treatment approaches to help clinicians make decisions regarding recently...
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