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爱思唯尔期刊精选全文<span class="ModTitle_Intro">[<a href="http://portal.elseviermed.cn/tabid/122/Default.aspx">栏目介绍</a>]</span>  爱思唯尔期刊精选全文[栏目介绍]
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American Journal of Medicine
中文标题: 肥胖与前列腺癌检测：三项国家调查的启示
英文标题: Obesity and Prostate Cancer Detection: Insights from Three National Surveys
作者: Niyati Parekh PhD, RD, Yong Lin PhDb Robert S. DiP...
全文: Background Previous studies suggest that obesity is associated with higher prostate cancer progression and mortality despite an association with lower prostate cancer incidence. This study aims...
Translational Research
中文标题: 干细胞疗法治疗1型糖尿病
英文标题: Stem cell approaches for the treatment of type 1 diabetes mellitus
作者: Ryan T. Wagner, Jennifer Lewis, Austin Cooney and ...
全文: Type 1 diabetes is characterized by near total absence of pancreatic b cells. Current treatments consisting of insulin injections and islet transplantation are clinically unsatisfactory. In order...
American Journal of Medicine
中文标题: 抑郁症与糖尿病足溃疡：一项前瞻性队列研究
英文标题: Depression and Incident Diabetic Foot Ulcers: A Prospective Cohort Study
作者: Lisa H. Williams MD, MS, Carolyn M. Rutter PhD, Wa...
全文: Objective To test whether depression is associated with an increased risk of incident diabetic foot ulcers. Methods The Pathways Epidemiologic Study is a population-based prospective cohort s...
Free Radical Biology and Medicine
中文标题: 氧化反应通过钙蛋白酶和caspase-3促进肌原纤维蛋白降解
英文标题: Oxidation enhances myofibrillar protein degradation via calpain and caspase-3
作者: Ashley J. Smuder, Andreas N. Kavazis, Matthew B. H...
全文: Oxidative stress has been linked to accelerated rates of proteolysis and muscle fiber atrophy during periods of prolonged skeletal muscle inactivity. However, the mechanism(s) that links oxida...
Journal of Cardiac Failure
中文标题: 静脉注射奈西立肽对心力衰竭患者心肌收缩力的急性效应
英文标题: Acute Effects of Intravenous Nesiritide on Cardiac Contractility in Heart Failure
作者: Sanjiv J. Shah MD and Andrew D. Michaels MD, MAS
全文: Background Although nesiritide is a potent vasodilator, studies using myocytes and isolated muscle strips have shown that recombinant B-type natriuretic peptide (BNP; nesiritide) decreases cont...
Contraception
中文标题: 左炔诺孕酮可抑制宫肌瘤细胞增值并诱导其凋亡
英文标题: The effect of patient gynecologic history on clinician contraceptive counseling
作者: hristine Dehlendorf, Rachel Ruskin, Philip Darney,...
全文: Background Contraceptive providers have an important influence on women's selection of contraception. Previous studies suggest that clinicians inappropriately limit use of intrauterine contracept...
Gynecologic Oncology
中文标题: mRNA可鉴别子宫癌的肿瘤亚型
英文标题: MicroRNA signatures differentiate uterine cancer tumor subtypes
作者: Elena S. Ratner, David Tuck, Christine Richter, Su...
全文: Objective Endometrial cancer (EC) is the most common gynecologic malignancy. Type I EC has a favorable prognosis, while type II ECs account for half of all treatment failures. Little knowledge of...
Free Radical Biology and Medicine
中文标题: 黄酮类物质的心血管作用并非仅只因其直接抗氧化活性因素
英文标题: Cardiovascular effects of flavonoids are not caused only by direct antioxidant activity
作者: Přemysl Mladěnka, Libuše Zatloukalová, Tomáš Filip...
全文: Epidemiological, as well as most in vivo, studies suggest that flavonoids have a positive influence on various cardiovascular diseases. Traditionally, these effects were only attributed to their a...
Journal of Cardiac Failure
中文标题: 心力衰竭患者贫血的纠正：红细胞生成刺激剂的有效性和安全性
英文标题: Correcting Anemia in Heart Failure: The Efficacy and Safety of Erythropoiesis-Stimulating Agents
作者: Patrick R. Lawler MD, Kristian B. Filion PhD and M...
全文: Background Randomized controlled trials (RCTs) evaluating the efficacy and safety of erythropoiesis-stimulating agents (ESAs), including erythropoietin and darbepoetin, among patients with chroni...
American Heart Journal
中文标题: 滥用安非他明的年轻成人心血管易形成主动脉夹层
英文标题: Aortic dissection in young adults who abuse amphetamines
作者: Arthur N. Westover MD, and Paul A. Nakonezny PhD
全文: Background Case reports suggest a relationship between amphetamine abuse/dependence and aortic dissection, but no population-based epidemiologic studies have examined this link. Our objective was t...
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病例分析 <span class="ModTitle_Intro_Right" id="EPMI_Home_MedicalCases_Intro_div" onclick="javascript:window.location='http://portal.elseviermed.cn/tabid/127/Default.aspx'" onmouseover="javascript:document.getElementById('EPMI_Home_MedicalCases_Intro_div').style.cursor='pointer';document.getElementById('EPMI_Home_MedicalCases_Intro_div').style.textDecoration='underline';" onmouseout="javascript:document.getElementById('EPMI_Home_MedicalCases_Intro_div').style.textDecoration='none';">[栏目介绍]</span>  病例分析 [栏目介绍]
多饮、多尿、全身乏力、闭经1年，体重增加、肝区不适半年——长海医院病例

曹晶珠  邹大进

 

解放军第二军医大学附属长海医院内分泌科

 

患者为中年女性，35岁，因“多饮、多尿、全身乏力、闭经1年，体重增加、肝区不适半年”于2008年8月入院。患者2007年感冒后出现多饮、多尿，每日饮水约10,000 ml，未予重视及诊治。2007年出现闭经，在外院妇产科就诊，先后予2次黄体酮肌肉注射，仍未来月经。半年前体重增加25 kg，肝区不适，肝功能示转氨酶升高。患者无便秘腹胀、无皮肤感染、无双下肢水肿，活动后稍感胸闷、气喘，夜尿增多，平均每小时1次。最大体重88.7 kg。既往史无特殊。月经史：初潮14岁，4/28～30，2008年6月。

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